A set of wireless monitoring and fault diagnosis system was established for the operation of 8 devices, 32 key pumps and 156 vibration measuring points in the first, second, third and fourth operation department of Dongying Haike Ruilin Chemical Co., Ltd. The system collects and monitors the vibration data of the equipment in real time, and uses intelligent alarm and early warning technology to strengthen the comprehensive evaluation of the equipment status, intelligent reasoning and fault diagnosis technology, so as to master the running status of the equipment in a timely manner. To provide an important basis for customer equipment maintenance decision, determine the best maintenance time of all parts of the equipment, prevent the occurrence of malignant accidents, and realize predictive maintenance.